Bioregistry Module - StackWave Affinity Biologics R&D LIMS

StackWave Affinity™

Bioregistry

Capture every reagent with appropriate context. Automatically connect oligos, plasmids, and proteins together by sequence, and analyze and annotate your antibody-based therapeutic sequences during registration. Review every detail from every Affinity module, all in one place.

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StackWave Affinity™ Bioregistry Module

The key to discovery is data that is FAIR: findable, accessible, interoperable, and reusable

Affinity's bioregistry is about more than just reagents - it's about getting the details right for every therapeutic concept on which your teams are working. Whether standard monoclonal or custom multispecific, cell-based or drug-conjugated, Affinity is designed to help your team translate from whiteboard to white paper.

The integrated and comprehensive nature of Affinity's modules brings together the details of every therapeutic candidate or assay-critical reagent: what experimental data has been captured, how much is left in inventory, even which ELN entries reference this particular reagent. With sequence-specific visualizations, you can review the parts, features, and annotations automatically identified by Affinity, or record your own. Support every team at every step of their process, all in one software solution.

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Image of plasmid circular map with restriction sites

Image of antibody sequence regions

Image of clone lead identification plot

Image of sequence alignment for antibody region

Image of operational antibody project data

Affinity in Action

Manage your entire process, from discovery to lead characterization

With Affinity, it's never been easier to collaborate effectively on drug discovery and development. Spend more of your time on discovery instead of data entry by using one solution that provides all of the tools you'll need. Request a demo or free trial today.

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Collaborate

Facilitate collaboration between discovery, production, and analytics teams

Integrate

Fully integrated, from target identification to lead characterization

Consolidate

Single source of truth for all assay data

Analyze

In-depth analysis of lead antibodies

Sequence Analysis
Phage Panning
Lead Characterization
Hybridoma Production

Sequence Analysis

Leverage Affinity’s built-in sequence analysis tools to identify the unique antibodies in your discovery campaign results without having to license or build a separate bioinformatics system. Additional sequence search tools take advantage of Affinity’s sequence and variable region databases to quickly find related sequences.

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Phage Panning

Phage panning allows you to narrow the enormous diversity represented by your phage libraries to a manageable set of antibodies for further study. Create visual designs of your phage panning experiment to track which combinations of antigens and other inputs produced the most promising leads. From the pools of phage output produced, generate sets of screening plates for assaying, sequencing, screening, and analysis.

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Lead Characterization

StackWave Affinity provides workflows for phage, hybridoma, and single B-cell campaigns, assay data management, sequence analysis, custom reporting, and plate generation in a single solution. These tools integrate seamlessly to help discovery teams quickly identify their most promising lead antibodies. Automation support for liquid handling platforms and assay data ingest allows for high-throughput screening of campaign results.

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Hybridoma Production

Manage the complexity of hybridoma campaigns with an actual animal study management solution that connects seamlessly with hybridoma plate generation. Generated plates can be screened, sequenced, filtered, and lead antibodies identified using an intuitive set of tools that combine assay data management, sequence analysis, and custom reporting.

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"StackWave gives us confidence in our leads by collecting all of the data about our potential therapeutics in one place and making that data actionable by allowing us to compare antibodies of interest."

"I worked with StackWave for ~4 years at my previous job to implement our LIMS. It was a great learning experience. We put in place an incredible system for our entire workflow, from plasmid registration to in-vivo study data registration."

"StackWave’s Platform allowed us to collaborate on our in-vivo studies in a web browser at home... I would highly recommend StackWave for therapeutic discovery teams looking to improve collaboration between teams."