StackWave Affinity™ Solutions

High Throughput Screening

Automatically associate assay data with appropriate antibodies to facilitate lead identification and chacterization

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StackWave Affinity™ High Throughput Screening

The continued miniaturization of screening assays into high-density plate formats and growth in the use of liquid handling platforms create opportunities for high-throughput screening of antibodies generated by a discovery campaign.

Affinity is designed to process large sets of screening data and to generate the automation scripts that drive liquid handler robots. Experimental data files can be imported directly from the instruments that produced them into Affinity's assay data management system. Captured assay data can then be combined into reports and used to filter down to the best set of lead antibodies. Every set is associated with the filters that produced it and mapped to new plates using a plate layout of your choice. The source-to-destination mappings can then be exported as scripts to produce the new set of plates on your liquid handling platform. If needed, the filtered plates can themselves be filtered again to produce an entirely new set, including by using Affinity's lead characterization capabilities to "collapse to uniques, selecting only the unique antibody sequences identified by sequence analysis to produce a new set of plates.

With support for the entire screening process in a single place regardless of scale and out-of-the-box workflows for phage, hybridoma, and single B-cell campaigns, Affinity handles any discovery campaign of any size from start to finish.

Click here to download the StackWave Affinity LIMS presentation

Image of plasmid circular map with restriction sites
Image of antibody sequence regions
Image of clone lead identification plot
Image of sequence alignment for antibody region
Image of operational antibody project data
Affinity in Action

Manage your entire process, from discovery to lead characterization

With Affinity, it's never been easier to collaborate effectively on drug discovery and development. Spend more of your time on discovery instead of data entry by using one solution that provides all of the tools you'll need. Request a demo or free trial today.

Collaborate

Facilitate collaboration between discovery, production, and analytics teams

Integrate

Fully integrated, from target identification to lead characterization

Consolidate

Single source of truth for all assay data

Analyze

In-depth analysis of lead antibodies

"StackWave gives us confidence in our leads by collecting all of the data about our potential therapeutics in one place and making that data actionable by allowing us to compare antibodies of interest."

"I worked with StackWave for ~4 years at my previous job to implement our LIMS. It was a great learning experience. We put in place an incredible system for our entire workflow, from plasmid registration to in-vivo study data registration."

"StackWave’s Platform allowed us to collaborate on our in-vivo studies in a web browser at home... I would highly recommend StackWave for therapeutic discovery teams looking to improve collaboration between teams."

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One Tool for Antibody Discovery