Hybridoma technology is an effective method for generating monoclonal antibodies, but the many steps involved make management of hybridoma discovery campaigns a complex task.  Affinity provides built-in management of hybridoma campaigns with an animal study management solution, starting from the creation of cohorts and immunization schedules all the way through to spleen collection, B-cell and myeloma fusion, and hybridoma clone plate generation. Clone plates can then be screened and filtered and their sequences analyzed using Affinity’s built-in assay data management, custom reporting, and sequence analysis tools. 

 

Managing animals, immunization schedules, and tissue specimens is a chore, but Affinity simplifies the entire process. Affinity’s built-in animal study solution includes a simplified hybridoma campaign management interface that allows teams to replace Excel files or external animal study software. Record cohort characteristics, cages and cage numbers, immunizations, and animal measurements in a single place. The scheduling system can be used to develop an appropriate immunization schedule and can export that schedule to your Google or Outlook calendar.

 

Hybridoma Study Scheduling Image

 

Assay and sequence data for hybridoma plates in Affinity can be used to rapidly identify a desired set of lead antibodies, and built-in sequence analysis tools eliminate the need for an external sequence analysis system. Instead of relying on Excel or another animal management program, Affinity’s fully-integrated hybridoma workflow saves time and money by providing a complete discovery solution in a single place.